Abstract Search

ra0001p258 | (1) | WCRB2014

Testicular chemical pollutants alter sperm vitality, motility, and morphology: comparative studies in the human and dog

Byers Andrew , Sumner Rebecca , Richardson Holly-May , Stratford Claire , Cammack Thomas , Moxon Rachel , Tomlinson Mathew , Naeem Asad , Craigon Jim , England Gary C W , Lea Richard

Introduction: Declining human and canine male fertility has been associated with exposure to environmental chemicals (ECs). We investigated the effects of ECs on canine and human sperm vitality, motility, and morphology.Methods: Mean canine testicular levels (MTL) of PCB153 and DEHP were 0.9±0.14 μg/kg (n=8) and 0.31±0.03 μg/g (n=5) respectively. Spermatozoa from dogs (n=7) and human donations (n=9,...

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ra0002p010 | (1) | SRF2015

Characterisation of the dog as a sentinel species for human exposure to endocrine disrupting chemicals

Sumner Rebecca , Byers Andrew , Taylor Oliver , Moxon Rachel , White Natasha , Craigon Jim , Zhang Zulin L , England¹ Gary C W , Lea Richard

Introduction: A temporal decline in canine male fertility parallels that reported in the human. Our hypothesis is that this is associated with exposure to environmental chemicals (ECs). We investigated i) a relationship between canine testicular chemical profiles and Sertoli cell numbers and ii) the effects of testicular concentrations of chemicals on sperm DNA fragmentation, motility and vitality.Methods: Canine adult testes (routine castrations) from t...

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Reproduction Abstracts

Testicular chemical pollutants alter sperm vitality, motility, and morphology: comparative studies in the human and dog

Characterisation of the dog as a sentinel species for human exposure to endocrine disrupting chemicals

BiosciAbstracts